DraCatUlaFrom the bottom up:

Initial sketch layer. This one is hidden once I’m done tracing the ink

Base colour layer. If there are colour gradients I put them here, such as the stripes on the tail and the pupils.

Multiply layer. Used for the shadows. I like the look of the abrupt shadows instead of a soft shade.

Screen layer. Used to brighten up some areas. As opposed to shadows, I like to make smudge these for smooth transitions.

Screen layer 2. Normally I put the highlights with the first screen layer, but I decided to keep them separate.

Ink layer.  Black lines traced from the initial sketch.